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The tumor node metastasis (TNM) staging system for breast cancer is an internationally accepted system used to determine the disease stage. This disease stage is a measure of the extent of disease, which is used to guide management and determine prognosis. The 7th edition of the TNM staging system and the evidence supporting it are described here (table 1). The 6th edition of the TNM staging system is included for comparison (table 2). The initial evaluation, clinical manifestations, diagnosis, treatment, and prognosis of breast cancer are reviewed elsewhere. (See "An overview of breast cancer and treatment for early stage disease" and "Initial staging work-up for women with a diagnosis of breast cancer" and "Clinical decisions in systemic adjuvant therapy for early breast cancer".) TNM STAGING SYSTEM — The tumor node metastasis (TNM) staging system for breast cancer is based upon a retrospective analysis of survival in diverse samples of patients representing all stages of disease. It reflects the clinical evaluation methods and treatments that are applied to the particular study population. Periodic revisions are necessary because advanced imaging techniques and treatments evolve and impact survival. The 7th edition of the TNM staging system is the most recent version (table 1) . It replaces the 6th edition of the TNM staging system (table 2) . REVISIONS IN BREAST CANCER STAGING — Observed survival rates for 211,645 breast cancer cases diagnosed in years 2001-2002 and entered into the National Cancer Data Base (Commission on Cancer of the American College of Surgeons and the American Cancer Society) were used to reevaluate the prognostic value of the TNM descriptors.
The End of Nihilism Until now, >50% present with Stage IV Everything is getting smaller Screening IS beneficial: smaller tumors Minimally Invasive Surgery: smaller incisions Stereotactic Radiotherapy: smaller radiation field Molecular Diagnostics ©2006 RUSH University Medical Center 2009 Estimated US Cancer Deaths* Men 290,890 Lung and bronchus Prostate Colon and rectum Pancreas Leukemia Non-Hodgkin’s lymphoma 32% 10% 10% 5% 4% 4% Women 272,810 25% Lung and bronchus 15% 10% 6% 6% 4% Breast Colon and rectum Ovary Pancreas Leukemia • ~160,440 patients will die of NSCLC in 2010 American Cancer Society. At: http://www.cancer.org/docroot/STT/stt_0.asp. Accessed October 27, 2009. ©2006 RUSH University Medical Center Lung Cancer Linked to Smoking JAMA May 27, 1950 Tobacco Smoking as a possible etiologic factor in bronchiogenic carcinoma. A study of six hundred and eighty-four proved cases Ernest L. Wynder and Evarts A. Graham ©2006 RUSH University Medical Center Cum. Risk of Lung CA in UK Men Data from Sirs Doll & Peto unequivocally demonstrates that the risk of lung CA after smoking never returns to normal Vineis, P. et al. JNCI 2004;96:99-106 Copyright restrictions may apply. ©2006 RUSH University Medical Center
Common depictions of those in prostitution are continually problematic. Portrayals of low moral fiber, hypersexuality, and a fouling effect on society dominate common representations of prostitution. These misconstructions tell a warped and inaccurate story of only one side of the sex industry—the supply. They also suggest that women in prostitution would exist without buyers in the sex market—the demand side of the sex trade has long been ignored, and, consequently, grossly misunderstood. This inconsistency in study and perception of the root causes of the sex trade industry has badly hindered the law’s and society’s understandings of a complicated issue. About the following, however, experts are certain: without the largely male1 demand for the purchase of sex, there would be no sex trade. It is only with a firm understanding of the role of demand for the purchase of sex that we can apprehend the reasons why the industry exists, why exploitation thrives within it, and what approaches we must take in order to end it. Experts continue to explore the complicated structures of oppression that foster the mostly male desire to buy sex. A former Merrill Lynch investment banker turned anti-modern slavery researcher and advocate, Siddharth Kara, plays an integral role in illuminating the economic dynamics that generate the sex trade and render slavery essential to the optimal profitability of the industry itself. Kara tells us the following in regards to the supply-demand economics that drive modern slavery: “Certain market forces create a demand for a product; other market forces create a supply to meet that demand.
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Rupal Hospital For Women is the pioneer centre of fertility care and treatment in South Gujarat since 35 years. With successful and busy practice in Gynecology and Obstetrics, the team of doctors at Rupal hospital have been successful in helping women’s to deliver more than 50,000 babies under their care and supervision. From pre-conception, to antenatal care, to the actual process of delivery and following it up with post-natal care, the medical staff and doctors are always ready to help you and stand by your side for the entire way. Our vision is to be a leading women and child health care provider, offering memorable birthing experience with a commitment to providing women with the highest quality and most advanced healthcare throughout all stages of their lives, from adolescence through menopause. At the end of the pregnancy journey you will be holding your precious baby in your hands and the discomforts of the past nine months will be a memory. For highest standard of pregnancy healthcare, from the stage of pre-conception to antenatal care to actual process of delivery, and to know about symptoms of pregnancy, complications of pregnancy you can contact us at http://www.rupalhospital.com or at http://www.rupalhospital.com/team.html or you can book an appointment at 91-261-2599128