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This work was aimed at providing preliminary findings that unraveled the promising potential of X. americana for the management of Mycobacterium bovis. The study tried to assess the anti-mycobacterial activity of Ximenia americana using the leave extract after extracting with methanol for 48 hours and the extract subjected to serial solvent partitioning with hexane, chloroform and n-butanol. The various solvent fractions obtained from the partitioning were screened against Mycobacterium bovis and the result showed hexane, chloroform and n-butanol extracts to inhibit the growth of the bacteria with a minimum concentration (MIC) of 3200 µg/ml, 1800 µg/ml and 3500 µg/ml respectively. The activity of the chloroform extract was found to be higher than the hexane and n-butanol as such Bio-assay guided fractionation of the chloroform extract was further carried out using column chromatography and nine fractions were obtained. http://www.scirj.org/jun-2014-paper.php?rp=P0614144
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