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About the CIES Football Observatory The CIES Football Observatory is a unique project initiated in 2005 by Drs Raffaele Poli and Loïc Ravenel under the name of the Professional Football Players Observatory (PFPO). Since 2011 it is one of the cornerstones of the broader CIES Sports Observatory project, dedicated to the statistical analysis of sport in all its diversity. Two annual reports are published for football. In January, the Demographic Study presents an in-depth analysis of club composition and player characteristics in 31 top division leagues of UEFA member countries. In June, the Annual Review analyses clubs and players in the big-5 European leagues from a demographic, economic and pitch performance perspective. Methodological rigour coupled with a deep knowledge of football guarantee high quality analyses at competitive rates. For more information: www.football-observatory.com About the CIES The International Centre for Sports Studies (CIES) is an independent study centre located in Neuchâtel, Switzerland. It was created in 1995 as a joint venture between the Fédération Internationale de Football Association (FIFA), the University of Neuchâtel, the City and State of Neuchatel. Using a multi-disciplinary approach CIES provides research, top-level education and consulting services to the sports world with the aim of overcoming the complexities of sport in today’s society and improving how it is governed and managed. For more information: www.cies.ch
Stem Cell Therapy in a Caprine Model of Osteoarthritis J. Mary Murphy,1 David J. Fink,1 Ernst B. Hunziker,2 and Frank P. Barry1 Objective. To explore the role that implanted mesenchymal stem cells may play in tissue repair or regeneration of the injured joint, by delivery of an autologous preparation of stem cells to caprine knee joints following induction of osteoarthritis (OA). Methods. Adult stem cells were isolated from caprine bone marrow, expanded in culture, and transduced to express green fluorescent protein. OA was induced unilaterally in the knee joint of donor animals by complete excision of the medial meniscus and resection of the anterior cruciate ligament. After 6 weeks, a single dose of 10 million autologous cells suspended in a dilute solution of sodium hyaluronan was delivered to the injured knee by direct intraarticular injection. Control animals received sodium hyaluronan alone. Results. In cell-treated joints, there was evidence of marked regeneration of the medial meniscus, and implanted cells were detected in the newly formed tissue. Degeneration of the articular cartilage, osteophytic remodeling, and subchondral sclerosis were reduced in cell-treated joints compared with joints treated with vehicle alone without cells. There was no evidence of repair of the ligament in any of the joints. Conclusion. Local delivery of adult mesenchymal stem cells to injured joints stimulates regeneration of meniscal tissue and retards the progressive destruction normally seen in this model of OA.
Joint science academies’ statement: Global response to climate change Climate change is real There will always be uncertainty in understanding a system as complex as the world’s climate. However there is now strong evidence that significant global warming is occurring1. The evidence comes from direct measurements of rising surface air temperatures and subsurface ocean temperatures and from phenomena such as increases in average global sea levels, retreating glaciers, and changes to many physical and biological systems. It is likely that most of the warming in recent decades can be attributed to human activities (IPCC 2001)2. This warming has already led to changes in the Earth's climate. The existence of greenhouse gases in the atmosphere is vital to life on Earth – in their absence average temperatures would be about 30 centigrade degrees lower than they are today. But human activities are now causing atmospheric concentrations of greenhouse gases – including carbon dioxide, methane, tropospheric ozone, and nitrous oxide – to rise well above pre-industrial levels. Carbon dioxide levels have increased from 280 ppm in 1750 to over 375 ppm today – higher than any previous levels that can be reliably measured (i.e. in the last 420,000 years). Increasing greenhouse gases are causing temperatures to rise; the Earth’s surface warmed by approximately 0.6 centigrade degrees over the twentieth century. The Intergovernmental Panel on Climate Change (IPCC) projected that the average global surface temperatures will continue to increase to between 1.4 centigrade degrees and 5.8 centigrade degrees above 1990 levels, by 2100.
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Kunci jawaban Babak FINAL Jenis soal : ESSAY 1. Kinerja bensin diukur berdasarkan nilai oktan (octane number) yaitu keberadaan senyawa 2,2,4 - trimetil pentane (isooktana) dengan nilai oktan 100, sedangkan nheptana nilai oktannya adalah nol. a. Gambarkan struktur 2,2,4 – trimetil pentane dan n – heptana (20 Point) Penyelesaian : b. Gambarkan semua isomer struktur n-heptana dan namai secara IUPAC (30 Point) Penyelesaian : c. Gambarkan struktur dan nama IUPAC alkena paling sederhana yang mempunyai isomer cis dan trans. (30 Point) Penyelesaian : d. Jelaskan pengertian bensin dengan angka oktan 75 % (20 Point) Penyelesaian : Angka oktan pada bensin ditentukan dengan adanya senyawa trimetil pentane dan nheptana dimana apabila pada bensin memiliki angka oktan 100 % maka pada besin tersebut terkandung senyawa trimetil pentane banding senyawa n-heptana yaitu 100 : 0, sehingga apabila bensin dengan angka oktan 75 % maka dalam bensin tersebut terkandung 75 % senyawa trimetil pentane dan 25 % senyawa n-heptana. 2. Reaksi : 2NOBr (g) 2NO (g) + Br2 (g) H = +16,1 kJ Diketahui : Tekanan awal NOBr = 0,65 atm. : NOBr telah terurai sebanyak 28% (Saat Kstb) (a) Tuliskan bentuk tetapan kesetimbangan, Kp. (10 poin) Penyelesaian : Kp [p NO ] 2 [p Br2 ] [p NOBr ] 2 (b) Tentukan tekanan parsial gas NOBr, NO, dan Br2 setelah tercapai keadaan kesetimbangan. (30 poin) Penyelesaian : 100 28 p NOBr 0,65 atm 0,468 atm 100 28 p NO 0,65 atm 0,182 atm 100 p Br2 28 2 100 0,65 atm 0,091 atm (c) Tentukan tekanan total sesudai tercapai kesetimbangan (20 poin) Penyelesaian : (100 28 ) (28 14 ) 114 p tot [ ] 0,65 atm 0,65 atm 0,741 atm 100 100 (d) Hitung nilai tetapan kesetimbangan, Kp pada temperatur tersebut. (20 poin) Penyelesaian :
Softail Oil Change From time to time I see question on the forum regarding doing an oil change on a Harley and more specifically about doing a scavenging oil change on a Softail. Since there didn't seem to be a good thread on doing an oil change with pictures, I thought I would write something up. This oil change was done on a 2001 Fat Boy. So, some of the tools and procedure may be different for your specific application. Tools Motorcycle lift 1/4" Allen head socket or long Allen head tool (for engine oil and transmission oil drain plugs) 3/8" Allen head socket or Allen head tool (transmission oil fill plug) 3/8" drive ratchet wrench 6" long 3/8" drive extension 3/8" drive universal joint (may or may not need depending on bike location on lift) 1/4" drive ratchet wrench T27 Torx head socket or torx head tool (primary cover screws) T40 Torx head socket or torx head tool (primary oil drain plug) Oil filter wrench Oil catch tool for filter (optional) Oil drain pan (preferably 2) Flashlight 3/8" Fuel / Oil line removal tool (Scavenging oil change ONLY) Clear tygon tubing (Scavenging oil change ONLY)
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Within the healthcare industry, the vaccine market was initially considered a low-profit venture but is currently perceived with renewed interest among industry circles due to its high demand with respect to emerging infectious diseases. Furthermore, an improved understanding of the immune system has paved new opportunities for developing novel preventive and therapeutic vaccines. This market research report evaluates the global vaccine market by technology class, types, end users, disease indication, and geography. Furthermore, the technology class is divided into eight segments, namely, live/attenuated, toxoid, conjugate, sub-unit, recombinant vector, DNA, synthetic, and dentritic vaccines. Of the above mentioned segments, sub-unit vaccine is the largest revenue segment; however, synthetic vaccines, recombinant vector vaccines, and DNA vaccines will be the fastest-growing segments. The global vaccine market was valued at $27 billion in the year 2012. At the end of 2013, the market is expected to be $32.05 billion and is poised to reach approximately $84 billion by 2022, growing at a CAGR of 11.36% from 2013 to 2022.
The first step in investing is defining your dreams for the future. If you are married or in a long-term relationship, spend some time together discussing your joint and individual goals. It's best to be as specific as possible. For instance, you may know you want to retire, but when? If you want to send your child to college, does that mean an Ivy League school or the community college down the street?
INSTALLATION GUIDELINES FOR: TRIUMPH DAYTONA 675 / (Kit # 69-3064): 1) Be sure to use Blue Loc-tite on all bolts and periodically check them for tightness. 2) Remove the stock stabilizer by finding each end of the stock unit. One end is attached to the lower side of the triple clamp and can be removed by using a 5mm Allen wrench accessing the bolt from the upper side of the bottom triple clamp. The other end of the stabilizer has a rubber boot covering the Heim joint. Roll the boot back and you can access the other 5mm Allen bolt. This bolt is some cases can be very tight, so as an option you can remove the upper radiator mount, which can be removed by pulling 3 small bolts. This just allows easier access to the Allen bolt that holds the rear of the stock stabilizer. Once the stock damper is removed the radiator bracket can be re-installed. 3) Remove the large main nut and washer that holds your triple clamp on. This is an odd-size nut (37.5mm) so you may need to use a crescent wrench to remove it, if you don’t have that size socket. 4) Install the new triple clamp damper mount (TC mount) over the steering stem with the “machined register” indexing over the back of your stock triple clamp. It’s machined to fit perfectly over the back edge of the triple clamp. 5) Be sure this TC mount is setting down flush on the triple clamp surface all the way around. Remove any obstructions that would not allow the TC mount to sit flush against your stock triple clamp surface. 6) Install the new 32mm main nut that we provide in the kit. This goes inside the recess on the TC mount and should be tightened to the recommended Torque setting from the factory. Normally a minimum of 50-80 ft lbs. 7) (Note: 32mm sockets are available from Sears at a reasonable price, should you not have one in your tool set). 8) Remove the (2) stock-front-tank retaining bolts. You will use the longer (6x30mm) bolts provided in the kit.