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Grafix® Demonstrates Overwhelming Efficacy in Landmark Stem Cell Study for the Treatment of Diabetic Foot Ulcers Grafix closes three times as many wounds as standard of care - the largest relative improvement ever reported in a multi-center, randomized, controlled clinical trial for DFU COLUMBIA, Md. - August 13,2013 - Osiris Therapeutics, Inc. (NASDAQ: OSIR), reported today that its multicenter, randomized, controlled clinical trial comparing the safety and effectiveness of Grafix® to standard of care in patients with chronic diabetic foot ulcers had met the pre-specified stopping rules for overwhelming efficacy as determined by the data monitoring committee during a planned interim analysis. For the primary endpoint, 62% of patients receiving Grafix had complete wound closure compared to only 21% (p<0.0001) of patients who received conventional treatment for their wounds - a relative improvement of 191% and the largest ever reported from such a study. A total of 131 patients were enrolled with the interim analysis being conducted on the first 97 to complete the trial. The trial also reached statistical significance in favor of Grafix on all top-line secondary endpoints, demonstrating faster wound closure and a reduction in the number of treatments needed to achieve wound closure. In the crossover phase of the trial, patients whose wounds failed to close after 12 weeks of standard of care had an 80% closure rate when switched to Grafix. Importantly, patients randomized to receive standard of care were 74% more likely to experience an adverse event than those receiving Grafix (p=0.008). As a result, the blinded phase of the trial is being discontinued immediately and all patients randomized to the control arm will be offered treatment with Grafix. “Today, Osiris has established a new standard in diabetic wound care and has demonstrated to the world the tremendous impact stem cell products can have in medicine,” said C. Randal Mills, Ph.D., Chief Executive Officer. “Diabetic foot ulcers afflict 25% of all diabetics and are responsible for more hospitalizations than any other diabetic complication. With 25 million diabetics in the United States, the cost to our health care system is enormous. Through this rigorous study we have shown that Grafix can heal more patients, in less time, and with fewer complications.”
• Review this document before taking possession of your MacBook. • The Apple MacBook, power adapter, case, stored data, on campus network and Internet access, and any services that will be issued are the sole property of the Shelton School & Evaluation Center. • The equipment listed is on loan to the student for the period designated on the last page. At the end of the loan period, or upon withdrawal from the school, all equipment must be returned in good working order. • These technologies are on loan to the student and must be used in accordance with all school policies, any applicable laws, and this document. Refer to the Shelton Acceptable Use Policy for Technology in the Parent Handbook. • These technologies are provided for educational and instructional purposes only and are intended to support the learning objectives of the school. • Students and their parents/guardians are responsible for cost of repair or replacement which will be assessed in the event of lost or damaged equipment. • Use of these technologies is a privilege and not a right. Equipment to be issued • Apple MacBook Air 13” • Apple MacBook Air Power adapter • STM Carrying Case (for MacBook Air) Ownership and Installation of Apps • Students are not allowed to install software on their computer without specific permission from the Shelton Technology Department and/or Administration. • Students and parents may purchase software and request that it be installed. Tech Support will require documentation of valid licensing and any license codes or account logins necessary to complete the installation. • Personally purchased software should be appropriate for school and conform to School Policy regarding content. (See the Shelton Acceptable Use Policy for Technology in Parent Handbook). Students/parents retain ownership of personally purchased software but should...
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Setting up the wireless speaker adapter 1. Connect the power supply to the wireless speaker adapter. 2. Plug the power supply into an AC outlet. 3. Connect the wireless speaker adapter to powered speakers or an AV receiver using the included Y-cable. 4. Press the connect button on the wireless speaker adapter to place it in Bluetooth® pairing mode. 5. The wireless speaker adapter connects to smart phones, tablets, and Bluetoothenabled computers. Put your Bluetooth device in pairing mode. (Refer to the documentation that comes with your device for pairing instructions.) If your Bluetooth device requests a security code, PIN, or pass code, enter 0000. The Bluetooth connection is made. You’re ready to play some music. Français 1. Conecta la fuente de alimentación al adaptador inalámbrico para altavoces. 2. Conecta la fuente de alimentación a una toma de corriente alterna. 3. Conecta el adaptador inalámbrico para altavoces a altavoces amplificados o un receptor AV mediante el cable en Y incluido. 4. Pulsa el botón de conexión en el adaptador inalámbrico para altavoces para colocarlo en el modo de emparejamiento Bluetooth®. 5. El adaptador inalámbrico para altavoces se puede conectar a teléfonos inteligentes, tabletas y computadoras con tecnología Bluetooth. Coloca el dispositivo Bluetooth en modo de emparejamiento. (Consulta la documentación que se suministra con el dispositivo para obtener instrucciones detalladas). Si el dispositivo Bluetooth solicita un código de seguridad, un PIN o una clave de acceso, escribe 0000. Se establecerá la conexión Bluetooth. Una vez establecida la conexión, ya podrás reproducir música.
1. Connect the power supply to the wireless speaker adapter. 2. Plug the power supply into an AC outlet. 3. Connect the wireless speaker adapter to powered speakers or an AV receiver using the included Y-cable. 4. Press the connect button on the wireless speaker adapter to place it in Bluetooth® pairing mode. 5. The wireless speaker adapter connects to smart phones, tablets, and Bluetooth-enabled computers. Put your Bluetooth device in pairing mode. (Refer to the documentation that comes with your device for pairing instructions.) If your Bluetooth device requests a security code, PIN, or pass code, enter 0000. The Bluetooth connection is made. You’re ready to play some music. 1. Schließen Sie das Stromkabel an den Adapter an. 2. Schließen Sie das Stromkabel an eine Steckdose an. 3. Schließen Sie den Wireless Speaker Adapter mithilfe des mitgelieferten Y-Kabels an Lautsprecher mit eigenem Stromanschluss oder an einen AV-Empfänger an. 4. Drücken Sie die Verbindungstaste auf dem Adapter, um ihn in den Bluetooth®-Pairing-Modus zu versetzen. 5. Der Wireless Speaker Adapter kann eine Verbindung zu Smartphones, Tablet-PCs und Bluetooth-fähigen Computern herstellen. Versetzen Sie Ihr Bluetooth-Gerät in den PairingModus. (In der Dokumentation zu Ihrem Gerät finden Sie Anweisungen zum Pairing.) Falls Ihr Bluetooth-Gerät Sie zur Eingabe eines Sicherheitscodes, einer PIN oder eines Passcodes auffordert, geben Sie 0000 ein. Die Bluetooth-Verbindung wurde hergestellt. Sie können jetzt Musik hören.
College Scholarship Enrollment Form Please submit this completed form to enroll or to report your 2013 sales. To enroll, you must sell at least $2,500 from January 1, 2013 to December 31, 2013. SALE INFORMATION Spring 2013 Face-to-Face Sales (Take Order): $ ______________ Spring 2013 Show & Sell: $ ______________ Fall 2013 Take Order: $ ______________ Fall 2013 Show & Sell: $ ______________ 2013 Online Sales (sell.trails-end.com): $ ______________ 2013 Total Sales $ ____________________ SCOUT INFORMATION (to be completed by Scout) Scout's Full Name: _______________________________________ Qualifying Year: ____________ Birth Date: ______ / ______ / ______ Social Security # (last four digits – for account payout): XXX-XX-___ ___ ___ ___ Street Address ______________________________________________ State: _______ City: _________________________ Zip Code: ______________ Email Address (account balance will be emailed to you): ___________________________________________________ Council Name: _______________________________ Council City & State: ______________________________ COUNCIL APPROVAL (to be completed by Council) Council Popcorn Staff Advisor (print name): ___________________________________________ Council Popcorn Staff Advisor’s Signature: ___________________________________________ You must have your Council Popcorn Staff Advisor's signature to add sales HOW TO ENROLL OR REPORT SALES Please email the following documents to firstname.lastname@example.org. Trail’s End does not accept faxes, zipped files, or files over 10MB. This form may be submitted by the Scout or Council. 1. This completed form signed by your Council Popcorn Staff Advisor. 2. A copy of each paper order form used in the spring and/or fall sale. 3. A copy of your online sales report from sell.trails-end.com.
Excerpt from the article: Beware of your credibility blind spots, says Cara Hale Alter, author of The Credibility Code: How to Project Confidence and Competence When it Matters Most (Meritus, 2012).
Pneumatic elevators provide a cost-friendly solution to your vertical mobility problem. While they rely on technology far more advanced than that of traditional elevator, they generate enormous savings though their exceptional design and small footprint.
Intellectual Property All Intellectual Property, as defined below, owned by or which is otherwise the property of Samsung or its respective suppliers relating to the SAMSUNG Phone, including but not limited to, accessories, parts, or software relating there to (the “Phone System”), is proprietary to Samsung and protected under federal laws, state laws, and international treaty provisions. Intellectual Property includes, but is not limited to, inventions (patentable or unpatentable), patents, trade secrets, copyrights, software, computer programs, and related documentation and other works of authorship. You may not infringe or otherwise violate the rights secured by the Intellectual Property. Moreover, you agree that you will not (and will not attempt to) modify, prepare derivative works of, reverse engineer, decompile, disassemble, or otherwise attempt to create source code from the software. No title to or ownership in the Intellectual Property is transferred to you. All applicable rights of the Intellectual Property shall remain with SAMSUNG and its suppliers. Open Source Software Some software components of this product incorporate source code covered under GNU General Public License (GPL), GNU Lesser General Public License (LGPL), OpenSSL License, BSD License and other open source licenses. To obtain the source code covered under the open source licenses, please visit: http://opensource.samsung.com.