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Save all warnings and instructions for future reference. The term "power tool" in the warnings refers to your mains-operated (corded) power tool or battery-operated (cordless) power tool. Work area safety 1. Keep work area clean and well lit. Cluttered or dark areas invite accidents. 2. Do not operate power tools in explosive atmospheres, such as in the presence of flammable liquids, gases or dust. Power tools create sparks which may ignite the dust or fumes. 3. Keep children and bystanders away while operating a power tool. Distractions can cause you to lose control. Electrical safety 4. Power tool plugs must match the outlet. Never modify the plug in any way. Do not use any adapter plugs with earthed (grounded) power tools. Unmodified plugs and matching outlets will reduce risk of electric shock. 5. Avoid body contact with earthed or grounded surfaces such as pipes, radiators, ranges and refrigerators. There is an increased risk of electric shock if your body is earthed or grounded. Hold the saw with both hands while working! One-handed use is extremely hazardous! This saw is to be used by properly trained operators only. Only for EU countries Do not dispose of electric equipment or battery pack together with household waste material! In observance of European Directive 2002/96/EC on waste electric and electronic equipment, 2006/66/EC on batteries and accumulators and waste batteries and accumulators and their implementation in accordance with national laws, electric equipment and battery pack that have reached the end of their life must be collected separately and returned to an environmentally compatible recycling facility.
Cushioned Shoes You should wear cushioned shoes if you are a runner who needs maximum midsole cushioning and minimum medial (arch-side) support. These shoes are best suited for biomechanically efficient runners (you don't overpronate), and midfoot or forefoot strikers. Runners who do best in cushioned shoes often have moderate to high arches. Motion Control Shoes You should wear motion-control shoes if you are a runner who overpronates moderately to severely. Motion-control shoes will give you maximum rearfoot control and extra support on the medial (arch) side of the foot. Motion-control shoes are also best suited for big or heavy runners who need plenty of support and durability. These runners often have low arches (flat feet). Performance Training Shoes You should wear performance-training shoes if you are a runner who wants a light, well-balanced shoe suitable for racing, speedwork, or daily training. These shoes are best-suited for fast, efficient runners who want to train in them. Moderate overpronators can also train and race in some of these shoes. Racing Shoes You should wear racing shoes if you have a biomechanically efficient stride, don't have any current injuries, and want an exceptionally fast, lightweight shoe for races. Many runners use performance training shoes or their regular training shoes for races. Stability Shoes You should wear stability shoes if you are a runner who needs medial (arch-side) support and good midsole cushioning. These shoes are best suited for runners who are mild to moderate overpronators, and/or need added support and durability. Trail Shoes...
Neutral (Cushioned) shoes...are most appropriate for neutral runners of all shapes and sizes who either do not pronate or roll slightly to the outside when they strike the ground (supinate) and have mid to high arches. Neutral shoes provide the most flexibility of any shoe. Stability shoes...are typically well-suited to the runner who has normal to mild overpronation and medium-to-low arches. They often have a medial post or multi-density midsole to provide a degree of pronation (see illustration below) control which can range from mild to heavy control. Motion control shoes...are highly rigid designed to limit severe over-pronation. They offer maximmum stability and medial support. Typically, they have an inner post and a multi-density or polyurethane midsole. They tend to be the heaviest, most durable, and most expensive running shoes. Motion-control shoes are geared toward the runner who tends to severely over-pronate and who has flat arches. Racing shoes...consist of spikes and flats used in cross country and track. Flats are lightweight shoes used for racing, usually on roads. They consist of minimal amounts of cushioning. Spikes are also used for racing, typically on grass or a track. Spikes usually have metal or ceramic “spikes” that screw into the bottom of the shoe to provide traction. Finding the right fit for spikes is based more on foot shape and feel rather than pronation.
Kevin Balke. Ph.D., P.E.. Texas Transportation Institute. Westin Park Central Hotel. Dallas, Texas. Page 2. ▻ Overview of ITS. ▻ TTI ITS Applications. ▻ Future ... Kevin Balke. Ph.D., P.E. Texas Transportation Institute Westin Park Central Hotel Dallas, Texas Overview of ITS TTI ITS Applications Future Applications of ITS ITS = Intelligent Transportation System Application of advanced surveillance, control, information, vehicle, and communications technologies to address safety, mobility and environmental issues Began as official program of USDOT in 1991 Traffic and Transit Management Road Weather Monitoring and Information Systems Commercial Vehicle Fleet Operations ...
PB Financial Group is the leading hard money lenders and bridge loans lenders in Los Angeles. And offer designed take control of finances and move businesses forward. For more details visit http://blog.pbfinancialgrp.com/understanding-bridge-loans/
STEM CELLS AND CEREBRAL PALSY Cerebral palsy (CP) is an umbrella term which includes several forms and levels of nonprogressive brain-related injury, which cause limitations in muscle control, movement and mobility (known as neuromotor impairment) and other symptoms that lead to physical disability. CP is caused by many factors, and can include infection before birth, premature birth and lack of oxygen around the time of birth. It is thought that the major common feature in CP is a lack of blood and oxygen to the brain during fetal development and/or delivery, known as a hypoxic-ischemic insult. The cells most vulnerable to this hypoxic-ischemic insult are oligodendrocytes, the support cells that wrap nerve cells (or neurons) with a protective white fat called myelin, hence the term white matter of the brain. Because of this myelin, neurons can send electrical signals efficiently throughout the body. Once oligodendrocytes die, the neurons are no longer protected and they eventually die. If myelin could be replaced before neurons die, neurons could be spared and motor impairments could be lessened. For this reason, scientists are investigating whether lost oligodendrocytes can be replaced with stem cells. Stem cells are unspecialized cells which can become specialized cells such as brain cells, heart cells or muscle cells. The process of developing into a specialized cell is known as differentiation. Stem cells can also multiply over and over again, a process known as proliferation. During the process of proliferation the stem cell either remains unspecialized or, under the right condition, can become a specialized cell such as a brain cell. Replacing neurons themselves would be like trying to rewire a giant switchboard with tens of thousands of ports but no labels, where improper connections could lead to pain. It is for this reason that the aim of many cell transplantation strategies now being tested is to replace lost oligodendrocytes rather than to make and successfully connect new neurons. Recent decades have seen advances in our knowledge of how to study and use stem cells. It is expected we will develop ways to transplant stem cells into damaged tissues to treat and cure injury and diseases like CP. From Mice to Humans...
Grafix® Demonstrates Overwhelming Efficacy in Landmark Stem Cell Study for the Treatment of Diabetic Foot Ulcers Grafix closes three times as many wounds as standard of care - the largest relative improvement ever reported in a multi-center, randomized, controlled clinical trial for DFU COLUMBIA, Md. - August 13,2013 - Osiris Therapeutics, Inc. (NASDAQ: OSIR), reported today that its multicenter, randomized, controlled clinical trial comparing the safety and effectiveness of Grafix® to standard of care in patients with chronic diabetic foot ulcers had met the pre-specified stopping rules for overwhelming efficacy as determined by the data monitoring committee during a planned interim analysis. For the primary endpoint, 62% of patients receiving Grafix had complete wound closure compared to only 21% (p<0.0001) of patients who received conventional treatment for their wounds - a relative improvement of 191% and the largest ever reported from such a study. A total of 131 patients were enrolled with the interim analysis being conducted on the first 97 to complete the trial. The trial also reached statistical significance in favor of Grafix on all top-line secondary endpoints, demonstrating faster wound closure and a reduction in the number of treatments needed to achieve wound closure. In the crossover phase of the trial, patients whose wounds failed to close after 12 weeks of standard of care had an 80% closure rate when switched to Grafix. Importantly, patients randomized to receive standard of care were 74% more likely to experience an adverse event than those receiving Grafix (p=0.008). As a result, the blinded phase of the trial is being discontinued immediately and all patients randomized to the control arm will be offered treatment with Grafix. “Today, Osiris has established a new standard in diabetic wound care and has demonstrated to the world the tremendous impact stem cell products can have in medicine,” said C. Randal Mills, Ph.D., Chief Executive Officer. “Diabetic foot ulcers afflict 25% of all diabetics and are responsible for more hospitalizations than any other diabetic complication. With 25 million diabetics in the United States, the cost to our health care system is enormous. Through this rigorous study we have shown that Grafix can heal more patients, in less time, and with fewer complications.”
Stem Cell Therapy in a Caprine Model of Osteoarthritis J. Mary Murphy,1 David J. Fink,1 Ernst B. Hunziker,2 and Frank P. Barry1 Objective. To explore the role that implanted mesenchymal stem cells may play in tissue repair or regeneration of the injured joint, by delivery of an autologous preparation of stem cells to caprine knee joints following induction of osteoarthritis (OA). Methods. Adult stem cells were isolated from caprine bone marrow, expanded in culture, and transduced to express green fluorescent protein. OA was induced unilaterally in the knee joint of donor animals by complete excision of the medial meniscus and resection of the anterior cruciate ligament. After 6 weeks, a single dose of 10 million autologous cells suspended in a dilute solution of sodium hyaluronan was delivered to the injured knee by direct intraarticular injection. Control animals received sodium hyaluronan alone. Results. In cell-treated joints, there was evidence of marked regeneration of the medial meniscus, and implanted cells were detected in the newly formed tissue. Degeneration of the articular cartilage, osteophytic remodeling, and subchondral sclerosis were reduced in cell-treated joints compared with joints treated with vehicle alone without cells. There was no evidence of repair of the ligament in any of the joints. Conclusion. Local delivery of adult mesenchymal stem cells to injured joints stimulates regeneration of meniscal tissue and retards the progressive destruction normally seen in this model of OA.
course of the investigation. On December 1, 2013, about 0719 eastern standard time, southbound Metro-North Railroad (Metro-North) passenger train number 8808 derailed at milepost 11.35 on track number 2 of the Metro-North Hudson Line in The Bronx, New York. Train movements on this line are governed by a traffic control system. The train originated in Poughkeepsie, New York with a destination of Grand Central Station in New York City. It consisted of seven passenger cars and one locomotive at the rear pushing the train. As a result of the derailment, 4 passengers died and 59 persons were transported to local hospitals for injuries. Metro-North estimated there were about 115 passengers on the train at the time of the derailment. Damage was estimated by Metro-North to be in excess of $9 million. The weather at the time of the accident was reported as 39° F with cloudy skies. Figure: Aerial view of accident scene National Transportation Safety Board (NTSB) investigators have completed the on-scene work in The Bronx. The investigation will continue at the NTSB headquarters in Washington, D.C. Preliminary results of the investigation include: The derailment occurred in a 6 degree left hand curve where speed was limited to 30 mph. Estimated train speed at the time of the derailment was at 82 mph. Detailed inspection and testing of the signal system, train brakes, and other mechanical equipment did not identify any anomalies. An inspection of the track in the derailment area did not identify any pre-accident anomalies. All cars on the train and the locomotive derailed. Between December 1 and 11, 2013, investigators completed interviews of train crews and first responders. Interview transcripts will be included in the public docket upon release. Locomotive event recorders were sent to the NTSB laboratory in Washington, D.C. for further analysis. The parties to the investigation include the Federal Railroad Administration, Metro-North Railroad, New York Public Transportation Safety Board, Teamsters Local 808, New York Police Department, New York Fire Department, and Bombardier Transportation. The Association of Commuter Rail Employees (ACRE) was initially designated as a party. However, because one of ACRE’s senior officials made unauthorized comments on the investigation to the media, ACRE was removed as a party on December 3, 2013.
Latihan Soal Sbmptn 2013 Tes Potensi Akademik (TPA) ----------------------------------------------------------------Created by ujiantulis.com (sebagian dari 5 Paket Latihan Sbmptn) Panitia SBMPTN Akan Menerapkan 5 Paket Soal Sbmptn Untuk Antisipasi perjokian dan kecurangan (Menurut Dr Anwar Effendi Kepala Humas dan Protokoler UNY/Kedaulatan Rakyat ) - Oleh karena itu ujiantulis.com memberikan 5 Paket Latihan Soal Sbmptn plus Pembahasannya untuk membantu kesuksesan peserta Sbmptn 2013. 1. Semua peserta SBMPTN 2013 mengerjakan Soal TPA. Sebagian peserta SBMPTN mengerjakan soal TPA kode 65. Simpulan yang tepat adalah ... (A) (B) (C) (D) (E) semua peserta SBMPTN mengerjakan Soal TPA, tidak mengerjakan soal TPA kode 65. semua peserta SBMPTN mengerjakan Soal TPA, mengerjakan soal TPA kode 65. semua peserta SBMPTN tidak mengerjakan Soal TPA, tidak mengerjakan soal TPA kode 65 sebagian peserta SBMPTN tidak mengerjakan Soal TPA, mengerjakan soal TPA kode 65. sebagian peserta SBMPTN yang mengerjakan Soal TPA, tidak mengerjakan soal TPA kode 65. ©ujiantulis.com 2. Ananda adalah lulusan SMAN 1 Bandung. Ananda akan mengikuti SBMPTN 2013. Banyak di antara para peserta yang akan mengikuti SBMPTN 2013 malas belajar. Ihsan adalah teman Ananda. Simpulan yang tepat adalah … (A)Ananda malas belajar. (B)Ihsan malas belajar. (C)Ihsan mungkin akan mengikuti SBMPTN 2013. (D)Semua teman Ihsan rajin. (E)Semua teman Ananda malas. 3. … berhubungan dengan JARUM, sebagaimana PETANI berhubungan dengan … (A) Dokter – pupuk (D) Penjahit – cangkul (B) Penjahit – padi (E) Perawat – sawah (C) Dokter – nelayan Copyright©ujiantulis.com all rights reserved | Distributed by info.sbmptn.web.id Page 1 4. … berhubungan dengan STETOSKOP, sebagaimana PELUKIS berhubungan dengan … (A) Dokter – kuas (B) Penyakit – pemandangan (C) Perawat – penyair (D) Pasien – galeri (E) Kesehatan – penghayatan 5. … berhubungan dengan SENAPAN, sebagaimana PETENIS berhubungan dengan … (A) Perang – medali (D) Tembakan – latihan (B) Tentara – raket (E) Perang – lapangan (C) Peluru – net 6. … berhubungan dengan KURSI, sebagaimana GULA berhubungan dengan … (A) Meja – gelas (D) Meja – kopi (B) Kayu – manis (E) Kayu – tebu (C) Kantor – pabrik 7. … berhubungan dengan KERAMIK, sebagaimana KERTAS berhubungan dengan … (A) Pot – buku (D) Keras – lunak (B) Lantai – majalah (E) Tanah liat – kayu (C) Tanah liat – buku ©ujiantulis.com 8. ... berhubungan dengan MOBIL, sebagaimana REL berhubungan dengan ... (A) Sopir – kereta api (D) Jalan raya – kereta api (B) Sopir – masinis (E) Ban – kereta api (C) Masinis – jalan raya 9. ... berhubungan dengan PANAS, sebagaimana ES berhubungan dengan ... (A) Kopi – teh (B) Api – dingin (C) Cuaca – minuman (D) Matahari – gula (E) Khatulistiwa – kutub 10. …. berhubungan dengan LAUT, sebagaimana PETANI berhubungan dengan ... (A) Perahu – cangkul (D) Ikan – padi (B) Jaring – cangkul (E) Nelayan – sawah (C) Nelayan – padi 11. …. berhubungan dengan TEPUNG, sebagaimana PAKAIAN berhubungan dengan ... Copyright©ujiantulis.com all rights reserved | Distributed by info.sbmptn.web.id Page 2 (A)Timbangan – penampilan (B)Mentega – celana (C)Roti – kain (D)Pasar – toko (E)Adonan – ukuran