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The Finnish study mentioned above finds that granting an employee Internet access at work increases his productivity by three percent in the service sector, but has no significant effect in manufacturing

Stem Cell Therapy: the ethical issues - Nuffield Council on Bioethics

Stem Cell Therapy: the ethical issues a discussion paper Published by Nuffield Council on Bioethics 28 Bedford Square London WC1B 3EG Telephone: Fax: Email: Website: 020 7681 9619 020 7637 1712 bioethics@nuffieldfoundation.org http://www.nuffieldfoundation.org/bioethics April 2000 © Nuffield Council on Bioethics 2000 All rights reserved. Apart from fair dealing for the purpose of private study, research, criticism or review, no part of the publication may be produced, stored in a retrieval system or transmitted in any form, or by any means, without prior permission of the copyright owners. Nuffield Council on Bioethics Professor Ian Kennedy (Chairman) Professor Martin Bobrow CBE (Deputy Chairman) Professor Tom Baldwin Professor Sir Kenneth Calman KCB FRSE* Reverend Professor Duncan Forrester DD Professor Brian Heap CBE FRS Mrs Rebecca Howard Lady Hornby Professor John Ledingham Mr Derek Osborn CB Professor Catherine Peckham CBE Professor Martin Raff FRS Mr Nick Ross Professor Herbert Sewell Professor Albert Weale FBA * (co-opted member of Council for the period of his Chairmanship of the Working Party on the ethics of healthcare-related research in developing countries) The terms of reference are as follows: 1 to identify and define ethical questions raised by recent advances in biological and medical research in order to respond to, and to anticipate, public concern; 2 to make arrangements for examining and reporting on such questions with a view to promoting public understanding and discussion; this may lead, where needed, to the formulation of new guidelines by the appropriate regulatory or other body; 3 in the light of the outcome of its work, to publish reports; and to make representations, as the Council may judge appropriate. The Nuffield Council on Bioethics is funded jointly by the Medical Research Council, the Nuffield Foundation and the Wellcome Trust Attendees of the Round Table meeting on Stem Cell Therapy: the ethical issues Professor Martin Bobrow CBE, Department of Medical Genetics, Cambridge Institute for Medical Research and Deputy Chairman of Nuffield Council on Bioethics Professor Tom Baldwin, Department of Philosophy, University of York, member of Nuffield Council on Bioethics Lady Hornby, Chairman of The Kingwood Trust, member of Nuffield Council on Bioethics...

Stem Cell Treatments For Cerebral Palsy Factsheet For - UCLA ...

STEM CELLS AND CEREBRAL PALSY Cerebral palsy (CP) is an umbrella term which includes several forms and levels of nonprogressive brain-related injury, which cause limitations in muscle control, movement and mobility (known as neuromotor impairment) and other symptoms that lead to physical disability. CP is caused by many factors, and can include infection before birth, premature birth and lack of oxygen around the time of birth. It is thought that the major common feature in CP is a lack of blood and oxygen to the brain during fetal development and/or delivery, known as a hypoxic-ischemic insult. The cells most vulnerable to this hypoxic-ischemic insult are oligodendrocytes, the support cells that wrap nerve cells (or neurons) with a protective white fat called myelin, hence the term white matter of the brain. Because of this myelin, neurons can send electrical signals efficiently throughout the body. Once oligodendrocytes die, the neurons are no longer protected and they eventually die. If myelin could be replaced before neurons die, neurons could be spared and motor impairments could be lessened. For this reason, scientists are investigating whether lost oligodendrocytes can be replaced with stem cells. Stem cells are unspecialized cells which can become specialized cells such as brain cells, heart cells or muscle cells. The process of developing into a specialized cell is known as differentiation. Stem cells can also multiply over and over again, a process known as proliferation. During the process of proliferation the stem cell either remains unspecialized or, under the right condition, can become a specialized cell such as a brain cell. Replacing neurons themselves would be like trying to rewire a giant switchboard with tens of thousands of ports but no labels, where improper connections could lead to pain. It is for this reason that the aim of many cell transplantation strategies now being tested is to replace lost oligodendrocytes rather than to make and successfully connect new neurons. Recent decades have seen advances in our knowledge of how to study and use stem cells. It is expected we will develop ways to transplant stem cells into damaged tissues to treat and cure injury and diseases like CP. From Mice to Humans...

Grafix® Demonstrates Overwhelming Efficacy in Landmark Stem ...

Grafix® Demonstrates Overwhelming Efficacy in Landmark Stem Cell Study for the Treatment of Diabetic Foot Ulcers Grafix closes three times as many wounds as standard of care - the largest relative improvement ever reported in a multi-center, randomized, controlled clinical trial for DFU COLUMBIA, Md. - August 13,2013 - Osiris Therapeutics, Inc. (NASDAQ: OSIR), reported today that its multicenter, randomized, controlled clinical trial comparing the safety and effectiveness of Grafix® to standard of care in patients with chronic diabetic foot ulcers had met the pre-specified stopping rules for overwhelming efficacy as determined by the data monitoring committee during a planned interim analysis. For the primary endpoint, 62% of patients receiving Grafix had complete wound closure compared to only 21% (p<0.0001) of patients who received conventional treatment for their wounds - a relative improvement of 191% and the largest ever reported from such a study. A total of 131 patients were enrolled with the interim analysis being conducted on the first 97 to complete the trial. The trial also reached statistical significance in favor of Grafix on all top-line secondary endpoints, demonstrating faster wound closure and a reduction in the number of treatments needed to achieve wound closure. In the crossover phase of the trial, patients whose wounds failed to close after 12 weeks of standard of care had an 80% closure rate when switched to Grafix. Importantly, patients randomized to receive standard of care were 74% more likely to experience an adverse event than those receiving Grafix (p=0.008). As a result, the blinded phase of the trial is being discontinued immediately and all patients randomized to the control arm will be offered treatment with Grafix. “Today, Osiris has established a new standard in diabetic wound care and has demonstrated to the world the tremendous impact stem cell products can have in medicine,” said C. Randal Mills, Ph.D., Chief Executive Officer. “Diabetic foot ulcers afflict 25% of all diabetics and are responsible for more hospitalizations than any other diabetic complication. With 25 million diabetics in the United States, the cost to our health care system is enormous. Through this rigorous study we have shown that Grafix can heal more patients, in less time, and with fewer complications.”

Study shows stem cell therapy using a patient's own bone marrow ...

TIME study mirrors Late TIME trial in confirming autologous stem cells obtained from bone marrow are safe but do not further improve the recovery of heart function following a heart attack MINNEAPOLIS, MN – November 6, 2012 – Administering autologous stem cells obtained from bone marrow either 3 or 7 days following a heart attack did not improve heart function six months later, reports a new clinical trial supported by the National Institutes of Health. The results of this trial, called TIME (Transplantation In Myocardial Infarction Evaluation), were presented by Jay Traverse, MD of the Minneapolis Heart Institute Foundation Tuesday, Nov. 6, at the 2012 Scientific Sessions of the American Heart Association in Los Angeles. The results of this trial mirror a previous, related study (LateTIME) which found that autologous bone marrow stem cell therapy given 2-3 weeks after a heart attack did not improve cardiac recovery. Both TIME and LateTIME were carried out by the Cardiovascular Cell Therapy Research Network (CCTRN), sponsored by the NIH’s National Heart, Lung, and Blood Institute. “The data presented by TIME do much to advance stem cell therapy research,” said Jay Traverse, MD of the Minneapolis Heart Institute Foundation and Principal Investigator of this study. “While this study did not provide a demonstrated cardiac benefit after six months, we still learned a great deal. Together, TIME and Late TIME have shown that stem cell therapy is safe, and they have set a baseline in terms of quantity of stem cells, type of stem cells, and severity of heart attack.” TIME enrolled 120 volunteers (avg. age 57) between July 2008 and February 2011; the participants all had moderate to severe impairment in their left ventricle and had undergone coronary stent placement as treatment for the heart attack. The participants were randomly assigned to one of four groups: day 3 stem cell, day 3 placebo (inactive cells), day 7 stem cell, or day 7 placebo. The CCTRN researchers developed a method of processing and purifying the stem cells from the bone marrow of each volunteer to ensure everyone received a uniform dose (150 million stem cells)...

METRO-NORTH RAILROAD CAREER OPPORTUNITIES

Summer Internship Opportunities Multiple opportunities are available. Work location will vary per position. Positions will be launched over the next 4-5 weeks and will be open until filled.  12 week program runs from 5/28-8/16.  Undergraduate pay rates are $15 per hour. Graduate and Law student pay rates are $17 per hour.  Free commuting on Metro-North Railroad.  Working knowledge of Microsoft Office Suite (Word, PowerPoint, Excel).  Position may require limited travel to our various New York and Connecticut locations.  To qualify for credit earning internships applicants must obtain approval from your Student Career Placement Office.  Good oral and written communication skills.  Good analytical and organization skills.  Excellent interpersonal and customer service skills to include dealing with the general public.  Flexibility to work as a team member, supportive of all Metro-North Railroad initiatives.  Must be dependable and a self-starter.  Monthly journal entries and final project assignment will be required as part of the Internship program.  A background check is required.  A physical abilities test and medical exam will be required for selected candidates at our NYC facility.  Students will be required to attend New Hire Orientation and Speaker Series meetings in our NYC facility.  All Interns are required to complete a Final Group Project and presentation. PREFERRED EDUCATION/EXPERIENCE Applicants must be a matriculating Undergraduate, Graduate, or Law student with a GPA of 2.5 or higher and a focus in the following fields:  Accounting  Communication/Journalism  Economics  Engineering (Civil, Mechanical, Electrical, Structural, Computer, Industrial)  Environmental studies  Finance  Hotel/Hospitality Management  Human Resources / Training/ Organizational Behavior / Industrial / Organizational Psychology  Information Technology/Computer Science ...

SMART SOLUTION Tes Potensi Akademik SBMPTN 2013

Rangkuman Materi SBMPTN 2013 SELEKSI BERSAMA MASUK PERGURUAN TINGGI NEGERI Disertai Teori Ringkas dan Pembahasan Soal Tes Potensi Akademik (TPA) Disusun Oleh : Pak Anang Kumpulan SMART SOLUTION dan TRIK SUPERKILAT Ringkasan Materi SBMPTN Tes Potensi Akademik (TPA) Penalaran Verbal (Sinonim, Antonim, dan Analogi) By Pak Anang (http://pak-anang.blogspot.com) A. PENALARAN VERBAL 1. SINONIM (Padanan Kata) Soal-soal sinonim, kemampuan yang dituntut adalah adik-adik mampu mencari arti dari sebuah kata pada pilihan jawaban yang tersedia. Tips agar adik-adik mudah menyelesaikan soal tentang sinonim adalah sering membaca. Nah, saat menemukan kata-kata asing, jangan ditinggalkan begitu saja, catat dan coba mencari padanan katanya di Kamus Besar Bahasa Indonesia. TRIK SUPERKILAT: Seringkali ada pilihan jawaban yang hampir mirip dengan soal. Biasanya jawaban ini adalah diberikan sebagai jawaban jebakan. Contoh soal sinonim: PARTIKELIR = .... A. Tukang parkir B. Partisan C. Partisi D. Swasta E. Enterprener Pembahasan: Jawaban B dan C mirip dengan kata yang digunakan pada soal. Biasanya ini mudah kita eliminasi sebagai jebakan jawaban..... Sehingga mempemudah kita dalam menjawab soal sinonim ini. Jawaban yang tepat adalah ”swasta”. 2. ANTONIM (Lawan Kata) Soal tentang antonim ini kebalikan dari sinonim. Dalam soal antonim adik-adik dituntut untuk mencari lawan kata dari soal yang diberikan. Contoh soal antonim: TERKATUNG A.Melayang B.Pasti C.Ombak D.Terperosok E.Terbenam

FOREX made easy draft 8
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Technical Analysis Technical analysis is the art of identifying patterns in the price movement of any security, such as forex, using historical trading data. Identifying these key patterns can help us understand where to buy and sell at given times. Technical analysis is a tool heavily used by many short to medium term traders, especially when there is little development in the market. Most market commentary and analyst picks use technical analysis incorporated with fundamental analysis. Why Is It Used? Technical analysis is used by nearly all traders at different scales and intensities. As a result, most technical movements are self-fulfilling as the market reacts according to the patterns. Fundamental analysis is the study of the intrinsic value of an investment. In forex, it entails looking at the economic conditions that affect the valuation of a nation's currency. The 4 major reports you can look at are: • Gross Domestic Product • Retail Sales • Industrial Production Index • Consumer Price Index The Two Basic Chart Movements To start with the basics, there are two types of chart movements in the markets. These are called Bull and Bear markets. Typical Bull Market Typical Bear Market The main feature of a bullish market is an upward moving market trend. Just like a bull, the market charges upwards. The main feature of a bearish market is the downward trending slope of the market. Most people refer to it as the bear swiping its paws down on the market, killing its upward momentum.

2013-2014 Scholarships & Grants - ROE #11

Scholarships & Grants This publication is not intended to be a complete listing of all scholarships and grants which are available. As the Regional Office of Education receives information on scholarships, we will update this listing. Students are urged to check with their high school counselor or the office of financial aid at the university or college they wish to attend. Many departments have special scholarships for students in that field of study and most schools have merit scholarships for academic achievement. To order free financial aid material, please contact the U.S. Department of Education. 2 Abbott and Fenner Scholarship: Abbott and Fenner Business Consultants Scholarship-Students are required to submit an essay on the topic that appears on the page attached to this link: http://www.abbottandfenner.com/scholarships.htm . Application: Available online at http://www.abbottandfenner.com/scholarships.htm . Application Deadline: June 14, 2014. Aldrich Green Scholarship: (Cumberland students ONLY) The Aldrich Green scholarship is offered to Cumberland high school seniors who aspire to continue their education at the college level. The award can be up to $1,000 and will be given to a student annually but will be distributed $500 per semester for the time he or she is enrolled in college. Special consideration will be given to students planning to return to Cumberland county to reside in and/or seek employment. Eligibility Requirements: The applicant must (1) have good academic standings, (2) have some school involvement (work experience may be considered) and (3) have goodcitizenship/behavior. Application: Is available online at www.firstneighbor.com/scholarship/scholarships.htm or contacting your local First Neighbor Bank. Application deadline: April 30, 2014. American Legion Auxiliary: Children of Warriors National Presidents’ Scholarship: This scholarship provides funds to assist children of those who have served. This award will be presented to 15 students annually who excel in academics and volunteer in their communities. Eligibility Requirements: The applicant must study only at a 4-year accredited college or university and may be used for tuition, books, fees, room and board. Candidates shall be daughters, stepdaughters, sons, stepsons, grandsons, step-grandsons, granddaughters, step-granddaughters, great-granddaughters, step-great granddaughters, great-grandsons, step-great grandsons of veterans who served in the...

2013-2014 scholarship guide for continuing & graduate students

2013-2014 SCHOLARSHIP GUIDE FOR CONTINUING & GRADUATE STUDENTS Scholarships at Old Dominion University have been established through the generosity of individuals, organizations and corporations to recognize outstanding academic performance and to assist students in pursuing their educational goals. Scholarship awards are based on a variety of criteria. For some awards, eligibility is entirely determined by academic merit or potential. Other requirements might include demonstrated financial need, field of study, state or city residency, graduation from a particular high school or participation in a specific program, organization or activity. Generally, recipients have earned at least a 3.4 grade point average (on a 4.00 scale) and are full-time, degree-seeking students.  All first-time freshmen and transfer students will automatically be considered for academic and endowed scholarships based on their admissions application.  The majority of scholarships offered to Old Dominion University returning students are based on information already known to the university.  The only students who should submit the Form for Continuing Students are  Students who have a CHANGE in scholarship eligibility according to the Criteria Checklist; a change in information refers to the data originally given on the admissions application or on subsequent scholarship forms. Please be aware that the criteria on the checklist may also change annually.

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